Quantitative real time PCR analysis of apoptotic gene expression in chronic lymphocytic leukemia patients and their relationships with chemosensitivity

Table 2 Relative gene expression of BCL2 and p53 of CLL patients (treated only) according to different treatment regimens, data expressed as Mean ± SEM

Treatment Regimen	No. of Patients	BCL2 expression	P value	P53 expression	P value
Clb	5	1.7 ± 0.93	.338	0.12 ± 0.05	0.647
Clb + P	10	4.2 ± 1.42	.542	0.12 ± 0.05	0.583
Clb + (Clb + P)	6	7.5 ± 4.16	.972	0.45 ± 0.27	0.162
FCR	11	11.5 ± 4.89	.402	0.20 ± 0.06	0.977
FCR+ Clb + (Clb + P)	5	4.1 ± 1.85	.592	0.08 ± 0.04	0.50
FCR + (Clb + P)	4	1.6 ± 0.71	.371	0.23 ± 0.17	0.903

Clb chlorambucil, P prednisolone, FCR: F fludarabine, C cyclophosphamide, R rituximab